The 40th Annual Fifth Third River Bank Run will take place in downtown Grand Rapids, Michigan, on Saturday, May 13, 2017. Featuring the largest 25K road race in the country, the event is also the USA 25 km Open Championships. More than 18,000 people are expected to participate in race day events including a 25K, 25K Handcycle, 25K Wheelchair, 10K, 5K and a 5K Community Walk.